English
norskBlar i forfatter "Grotle, Margreth"
Viser treff 1-20 av 22
-
Accumulation of health complaints is associated with persistent musculoskeletal pain two years later in adolescents: The Fit Futures Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-29)There is limited knowledge on the association between different health complaints and the development of persistent musculoskeletal pain in adolescents. The aims of this study were to assess whether specific health complaints, and an accumulation of health complaints, in the first year of upper-secondary school, were associated with persistent musculoskeletal pain 2 years later. We used data from a ... -
Accuracy of neuropathic pain measurements in patients with symptoms of polyneuropathy: validation of painDETECT, Self-Completed Leeds Assessment of Neuropathic Symptoms and Signs, and Douleur Neuropathique 4
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-10)Pain is a common symptom in patients referred to polyneuropathy assessment. Diagnostic evaluation and choice of treatment may depend on whether the pain is likely to be neuropathic or not. This study aimed to investigate the diagnostic accuracy of 3 tools commonly used to differentiate between neuropathic and nonneuropathic pain. To accomplish this, we included patients with bilateral distal lower ... -
Amoxicillin did not Reduce Modic Change Oedema in Patients with Chronic Low Back pain - subgroup Analyses of a Randomised Trial (the AIM study)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-12)<p><b> Study Design. </b> Exploratory subgroup analyses of a randomised trial (Antibiotics In Modic changes (AIM) study). <p><b> Objective. </b> To assess the effect of amoxicillin versus placebo in reducing Modic change (MC) oedema in patients with chronic low back pain (LBP). <p><b> Summary of Background Data. </b> The AIM study showed a small, clinically insignificant effect of ... -
Anterior surgical treatment for cervical degenerative radiculopathy: a prediction model for non-success
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-08)Purpose By using data from the Norwegian Registry for Spine Surgery, we wanted to develop and validate prediction models for non-success in patients operated with anterior surgical techniques for cervical degenerative radiculopathy (CDR).<p> <p>Methods This is a multicentre longitudinal study of 2022 patients undergoing CDR surgery and followed for 12 months to fnd prognostic models for non-success ... -
Antibiotic treatment In patients with chronic low back pain and Modic changes (the AIM study): study protocol for a randomised controlled trial.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-15)Background: <br>A previous randomised controlled trial (RCT) of patients with chronic low back pain (LBP) and vertebral bone marrow (Modic) changes (MCs) on magnetic resonance imaging (MRI), reported that a 3-month, high-dose course of antibiotics had a better effect than placebo at 12 months’ follow-up. The present study examines the effects of antibiotic treatment in chronic LBP patients with ... -
Behandlingsrater for ryggkirurgi i Norge og Helse Nord 2014-18
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-23)<i>BAKGRUNN</i> - Formålet med denne studien var å undersøke om behandlingstilbudet innen ryggkirurgi i Helse Nord er i henhold til den vedtatte funksjonsfordelingen mellom sykehusene i regionen, og om det er geografisk variasjon i tilbudet. Vi undersøkte derfor behandlingsrater i Norge og Helse Nord, samt egendekning i Helse Nord, og vurderte aktiviteten i regionen.<p> <p><i>MATERIALE OG METODE</i> ... -
Can a Successful Outcome After Surgery for Lumbar Disc Herniation Be Defined by the Oswestry Disability Index Raw Score?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-06)<i>Study Design</i>: Prospective multicenter cohort study.<p><p> <i>Objective</i>: To investigate (1) the discriminative ability and cutoff estimates for success 12 months after surgery for lumbar disc herniation on the Oswestry Disability Index (ODI) raw score compared with a change and a percentage change score and (2) to what extent these clinical outcomes depend on the baseline disability.< ... -
Cervical spine surgery in the Northern Norway Regional Health Authority area in 2014-18
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-24)<p>BAKGRUNN - Kunnskap om variasjon i behandlingsrater er nødvendig for å vurdere om tilgangen til helsetjenester er likeverdig. Formålet med denne studien var å undersøke rater for kirurgisk behandling av degenerative nakkelidelser i Norge og Helse Nord, samt egendekningen i Helse Nord, og å vurdere aktiviteten i regionen. <p>MATERIALE OG METODE - Vi inkluderte operasjoner registrert i Norsk ... -
Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - Secondary analyses of a randomised, placebo-controlled trial (the AIM study)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-13)<i>Background</i> - Randomised trials on antibiotic treatment for patients with chronic low back pain and vertebral endplate changes visible on MRI (Modic changes) have shown mixed results. A possible explanation might be a real treatment effect in subgroups of the study populations. The purpose of the present study was to explore potential clinical effect modifiers of 3-months oral amoxicillin ... -
Clinical improvement after surgery for degenerative cervical myelopathy; A comparison of Patient-Reported Outcome Measures during 12-month follow-up
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-08)Object - Although many patients report clinical improvement after surgery due to degenerative cervical myelopathy, the aim of intervention is to stop progression of spinal cord dysfunction. We wanted to provide estimates and assess achievement rates of Minimal Clinically Important Difference (MCID) at 3- and 12-month follow-up for Neck Disability Index (NDI), Numeric Rating Scale for arm pain (NRS-AP) ... -
Comparison of the SF6D, the EQ5D, and the oswestry disability index in patients with chronic low back pain and degenerative disc disease
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Background: The need for cost effectiveness analyses in randomized controlled trials that compare treatment options is increasing. The selection of the optimal utility measure is important, and a central question is whether the two most commonly used indexes - the EuroQuol 5D (EQ5D) and the Short Form 6D (SF6D) – can be used interchangeably. The aim of the present study was to compare change ... -
Complications, reoperations, readmissions, and length of hospital stay in 34 639 surgical cases of lumbar disc herniation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-01)<i>Aims</i>: The aims of this study were to determine the rates of surgical complications, reoperations, and readmissions following herniated lumbar disc surgery, and to investigate the impact of sociodemographic factors and comorbidity on the rate of such unfavourable events.<p> <p><i>Patients and Methods</i>: This was a longitudinal observation study. Data from herniated lumbar disc ... -
Criteria for failure and worsening after surgery for lumbar disc herniation: a multicenter observational study based on data from the Norwegian Registry for Spine Surgery
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-14)PURPOSE: In clinical decision-making, it is crucial to discuss the probability of adverse outcomes with the patient. A large proportion of the outcomes are difficult to classify as either failure or success. Consequently, cutoff values in patient-reported outcome measures (PROMs) for "failure" and "worsening" are likely to be different from those of "non-success". The aim of this study was to identify ... -
Criteria for success after surgery for cervical radiculopathy—estimates for a substantial amount of improvement in core outcome measures
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-02)<i>Background context</i> - Defining clinically meaningful success criteria from patient-reported outcome measures (PROMs) is crucial for clinical audits, research and decision-making.<p> <p><i>Purpose</i> - We aimed to define criteria for a successful outcome 3 and 12 months after surgery for cervical degenerative radiculopathy on recommended PROMs.<p> <p><i>Study design</i> - Prospective ... -
Effectiveness of adding motivational interviewing or a stratified vocational advice intervention to usual case management on return to work for people with musculoskeletal disorders: The MI-NAV randomised controlled trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-25)<b><p>Objectives:</b> To evaluate if adding motivational interviewing (MI) or a stratified vocational advice intervention (SVAI) to usual case management (UC), reduced sickness absence over 6 months for workers on sick leave due to musculoskeletal disorders. <b><p>Methods:</b> We conducted a three-arm parallel pragmatic randomised controlled trial including 514 employed workers (57% women, ... -
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-16)<p><i>Objective - </i>To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes). <p><i>Design - </i>Double blind, parallel group, placebo controlled, multicentre trial. <p><i>Setting - </i>Hospital outpatient clinics at six hospitals in Norway. <p><i>Participants ... -
Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-01)Objectives: The objective of this study was to estimate the minimal important change (MIC) and responsiveness of core patient reported outcome measures for chronic low back pain (LBP) and Modic changes.<p> <p>Study Design and Setting: In the Antibiotics in Modic changes (AIM) trial we measured disability (RMDQ, ODI), LBP intensity (NRS) and health-related quality of life (EQ5D) electronically at ... -
A nationwide study of patients operated for cervical degenerative disorders in public and private hospitals
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-27)During the last decades, there has been an increase in the rate of surgery for degenerative disorders of the cervical spine and in the use of supplementary private health insurance. Still, there is limited knowledge about the diferences in characteristics of patients operated in public and private hospitals. Therefore, we aimed at comparing sociodemographic-, clinical- and patient management data ... -
A prognostic model for failure and worsening after lumbar microdiscectomy: a multicenter study from the Norwegian Registry for Spine Surgery
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-10)<i>Objective</i> - To develop a prognostic model for failure and worsening 1 year after surgery for lumbar disc herniation.<br><br> <i>Methods</i> - This multicenter cohort study included 11,081 patients operated with lumbar microdiscectomy, registered at the Norwegian Registry for Spine Surgery. Follow-up was 1 year. Uni- and multivariate logistic regression analyses were used to assess potential ... -
The rates of lumbar spinal stenosis surgery in Norwegian public hospitals: a threefold increase from 1999 to 2013
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-17)<p><i>Study Design</i>: Retrospective administrative database study.</p> <p><i>Objective</i>: To assess temporal and regional trends, and length of hospital stay, in lumbar spinal stenosis (LSS) surgery in Norwegian public hospitals from 1999 to 2013.</p> <p><i>Summary of Background Data</i>: Studies from several countries have reported increasing rates of LSS surgery over the last decades. ...
